Academic papers relating to L2HGA



"an inherited disease of Staffordshire Bull Terriers and other breeds"



Abramson CJ, Platt SR, Jakobs C, Verhoeven NM, Dennis R, L. Garosi L and Shelton GD, (2003b) l-2-Hydroxyglutaric aciduria in Staffordshire Bull Terriers, J Vet Internal Med 17:551–556.


Dodman, N.H., Bronson, R., Gliatto, J. (1993). Tail Chasing in a Bull Terrier. Journal of the American Veterinary Medical Association 202: 758-760.


Dodman NH, Knowles KE, Shuster L, Moon-Fanelli AA, Tidwell AS, Keen CL. (1996) Behavioral changes associated with suspected complex partial seizures in bull terriers.Journal of the American Veterinary Medical Association 208(5):688-091.


Garosi LS, Penderis J, McConnell JF, Jakobs C. L-2-hydroxyglutaric aciduria in a West Highland white terrier. Vet Rec. 2005 Jan 29;156(5):145-7.


Moon-Fanelli AA, Dodman NH. (1998) Description and development of compulsive tail chasing in terriers and response to clomipramine treatment. J Am Vet Med Assoc. 212(8):1252-7. PMID: 9569164


Penderis J, Calvin J, Abramson C, Jakobs C, Pettitt L, Binns MM, Verhoeven NM, O'Driscoll E, Platt SR, Mellersh CS. (2007) L-2-hydroxyglutaric aciduria: characterisation of the molecular defect in a spontaneous canine model. J Med Genet. 44(5):334-40.


Sanchez-Masian DF, Artuch R, Mascort J, Jakobs C, Salomons G, Zamora A, Casado M, Fernandez M, Recio A, Lujan A. L-2-hydroxyglutaric aciduria in two female Yorkshire terriers. J Am Anim Hosp Assoc. 2012 Sep-Oct;48(5):366-71


Scurrell E, Davies E, Baines E, Cherubini GB, Platt S, Blakemore W, Williams A, Schöniger S. (2008) Neuropathological findings in a Staffordshire bull terrier with l-2-hydroxyglutaric aciduria. J Comp Pathol. 138(2-3):160-4.   online abstract


Short AD, Dunne A, Lohi H, Boulton S, Carter SD, Timofte D, Ollier WE. Characteristics of epileptic episodes in UK dog breeds: an epidemiological approach. Vet Rec. 2011 Jul 9;169(2):48.   online abstract





Treatment for dogs with fits


Canine Epilepsy Guardian Angels is a useful web site for owners of dogs with fits is  - its a little dated now, there are some new medications it doesn't mention, but for general support its excellent, if a bit alternative in places:















Link button